Inhibition of cysteine-serine-rich nuclear protein 1 ameliorates ischemia–reperfusion injury during liver transplantation in an MAPK-dependent manner

Abstract Hepatic ischemia–reperfusion injury (HIRI) is a critical pathophysiological process during liver transplantation (LT). Multiple genes and signal pathways are dysregulated during HIRI. This study aims to identify genes as potential therapeutic targets for ameliorating HIRI. Datasets containi...

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Bibliographic Details

Published in:	Molecular Biomedicine
Main Authors:	Zhoucheng Wang, Wenwen Ge, Xinyang Zhong, Shizheng Tong, Shusen Zheng, Xiao Xu, Kai Wang
Format:	Article
Language:	English
Published:	Springer 2024-06-01
Subjects:	Liver transplantation Hepatic ischemia–reperfusion injury (HIRI) Cysteine-serine-rich nuclear protein-1 (CSRNP1) Mitogen-activated protein kinases Nanoparticles
Online Access:	https://doi.org/10.1186/s43556-024-00185-z