Small extracellular vesicles derived from auricular chondrocytes promote secretion of interleukin 10 in bone marrow M1-like macrophages

Introduction: Elucidation of the paracrine interaction between chondrocytes and macrophages is useful for understanding the mechanisms of cartilage regeneration. Extracellular vesicles are granular substances with a diameter of approximately 150 nm, surrounded by a phospholipid bilayer membrane. In...

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Bibliographic Details

Published in:	Regenerative Therapy
Main Authors:	Tetsuya Kobatake, Yoshiyuki Miyamoto, Yuko Fujihara, Hideto Saijo, Kazuto Hoshi, Atsuhiko Hikita
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Subjects:	Macrophages Chondrocytes Extracellular vesicles Paracrine Anti-inflammatory cytokine
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352320425000094