Bordetella spp. utilize the type 3 secretion system to manipulate the VIP/VPAC2 signaling and promote colonization and persistence of the three classical Bordetella in the lower respiratory tract

IntroductionBordetella are respiratory pathogens comprised of three classical Bordetella species: B. pertussis, B. parapertussis, and B. bronchiseptica. With recent surges in Bordetella spp. cases and antibiotics becoming less effective to combat infectious diseases, there is an imperative need for...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Nicholas J. First, Jose Pedreira-Lopez, Manuel R. F. San-Silvestre, Katelyn M. Parrish, Xiao-Hong Lu, Monica C. Gestal
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	Bordetella bronchiseptica Bordetella pertussis Bordetella parapertussis Bordetella VIP (vasoactive intestinal peptide) type 3 secretion system
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1111502/full