Impact of creatine supplementation on inflammation: evidence from a systematic review and meta-analysis of randomized double-blind placebo trials

IntroductionCreatine supplementation is widely recognized for its ergogenic effects on strength and body composition. Recent studies have explored its potential anti-inflammatory properties, particularly in exercise-induced stress and aging-related chronic inflammation. However, results across rando...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Kell Mazzini Ribeiro de Camargo, Alejandro Bruna-Mejías, Juan José Valenzuela-Fuenzalida, Luana A. Gonzaga, Sandra Maria Barbalho, Alexandre L. Barroca, Andrey A. Porto, Rodrigo D. Raimundo, Luiz Carlos de Abreu, Vitor E. Valenti
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2026-02-01
Subjects:	creatine CRP cytokines IL-6 inflammation meta-analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1743603/full