Place in therapy of key treatments for platinum-sensitive, relapsed, extensive-stage small cell lung cancer with a focus on lurbinectedin: a narrative review with case studies

Background: Virtually all patients with extensive-stage small cell lung cancer (SCLC) develop resistance to firstline platinum-based chemoimmunotherapy and experience relapse. Second-line therapy is therefore an integral part of the treatment paradigm. Methods: Evidence was reviewed for key sec...

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Bibliographic Details

Published in:	Drugs in Context
Main Authors:	Leonid Shunyakov, Firas B Badin, Judith Hafer, David König, Patrizia Froesch, Laurent Greillier
Format:	Article
Language:	English
Published:	BioExcel Publishing Ltd 2025-10-01
Subjects:	extensive-stage small cell lung cancer lurbinectedin platinum rechallenge second-line chemotherapy topotecan
Online Access:	https://www.drugsincontext.com/place-in-therapy-of-key-treatments-for-platinum-sensitive-relapsed-extensive-stage-small-cell-lung-cancer-with-a-focus-on-lurbinectedin-a-narrative-review-with-case-studies/