Differential Sensitivity to MEK Inhibitors Highlights Distinct Entosis Mechanisms in BxPC3 and MCF7 Cells

Entosis is a form of cell-in-cell interaction observed in epithelial cancers, characterized by the internalization of one cell into another. This process is initiated by cell detachment, cadherin-mediated homotypic adhesion, and the formation of an entotic vacuole. Mechanistically, entosis is driven...

Full description

Bibliographic Details

Published in:	Cells
Main Authors:	Paweł Tyrna, Julia Kostro, Monika Olszanecka, Piotr Szukało, Izabela Młynarczuk-Biały
Format:	Article
Language:	English
Published:	MDPI AG 2025-09-01
Subjects:	entosis MEK Rac1B adhesion cancer invasion cell migration
Online Access:	https://www.mdpi.com/2073-4409/14/19/1500