A statistical mechanics investigation of unfolded protein response across organisms

Abstract Living systems rely on coordinated molecular interactions, especially those related to gene expression and protein activity. The Unfolded Protein Response is a crucial mechanism in eukaryotic cells, activated when unfolded proteins exceed a critical threshold. It maintains cell homeostasis...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Nicole Luchetti, Keith M. Smith, Margherita A. G. Matarrese, Alessandro Loppini, Simonetta Filippi, Letizia Chiodo
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-11-01
Subjects:	Endoplasmic reticulum stress Complex networks Protein-protein interactions Network analysis
Online Access:	https://doi.org/10.1038/s41598-024-79086-8