Generation and characterization of six human induced pluripotent stem cell lines (hiPSCs) from three individuals with SSADH Deficiency and CRISPR-corrected isogenic controls

Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD) is an ultra-rare autosomal recessive neurometabolic disorder caused by ALDH5A1 mutations presenting with autism and epilepsy. Here, we report the generation and characterization of human induced pluripotent stem cells (hiPSCs) derived from fibr...

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Bibliographic Details

Published in:	Stem Cell Research
Main Authors:	Wardiya Afshar-Saber, Cidi Chen, Nicole A. Teaney, Kristina Kim, Ziqin Yang, Federico M. Gasparoli, Darius Ebrahimi-Fakhari, Elizabeth D. Buttermore, Ivy Pin-Fang Chen, Phillip L. Pearl, Mustafa Sahin
Format:	Article
Language:	English
Published:	Elsevier 2024-06-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506124001223