Brain-expressed 3’UTR extensions strengthen miRNA cross-talk between ion channel/transporter encoding mRNAs

Why protein-coding genes express transcripts with longer 3’untranslated regions (3’UTRs) in the brain rather than in other tissues remains poorly understood. Given the established role of 3’UTRs in post-transcriptional regulation of transcript abundance and their recently highlighted contributions t...

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Bibliographic Details
Published in:Frontiers in Genetics
Main Authors: Claudia C Wehrspaun, Chris P Ponting, Ana C Marques
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00041/full