Divergent gene signatures and neutrophil enrichment in lymph nodes of inflammatory arthritis patients

Abstract Background Lymph node (LN) studies in anti-cyclic citrullinated protein antibodies (ACPA) positive rheumatoid arthritis (RA) patients have revealed notable alterations in adaptive immune cell populations. However, it remains unclear whether similar changes occur in seronegative inflammatory...

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Bibliographic Details

Published in:	Arthritis Research & Therapy
Main Authors:	Aoife M. O’Byrne, Janne W. Bolt, Chaja M.J. van Ansenwoude, Martijn van der Heijde, Johanna F. Semmelink, Aldo Jongejan, Perry D. Moerland, Mario Maas, Marleen G.H. van de Sande, Lisa G.M. van Baarsen
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Subjects:	Inflammatory arthritis Neutrophils Lymph nodes Pathogenesis
Online Access:	https://doi.org/10.1186/s13075-025-03557-0