Dynamic changes of intracellular signals in ATTR Tyr114Cys amyloidosis

Hereditary transthyretin (TTR) amyloidosis (ATTRv amyloidosis) is an autosomal dominant disease caused by various TTR mutations. Despite the fact that ATTR Tyr114Cys (p.Tyr134Cys) amyloidosis (tyrosine to cysteine at codon 114) exhibits poorer prognosis than other ATTRv amyloidosis and leads to deat...

Full description

Bibliographic Details

Published in:	Biochemistry and Biophysics Reports
Main Authors:	Kenta Ouchi, Takeshi Masuda, Kou Yonemaru, Kaori Isono, Yuki Ohya, Nobuaki Shiraki, Masayoshi Tasaki, Yukihiro Inomata, Mitsuharu Ueda, Takumi Era, Shoen Kume, Yukio Ando, Hirofumi Jono
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Subjects:	ATTR amyloidosis Transthyretin Induced pluripotent stem cells Proteomic analysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405580825000998