Filamin C regulates skeletal muscle atrophy by stabilizing dishevelled-2 to inhibit autophagy and mitophagy

FilaminC (Flnc) is a member of the actin binding protein family, which is preferentially expressed in the cardiac and skeletal muscle tissues. Although it is known to interact with proteins associated with myofibrillar myopathy, its unique role in skeletal muscle remains largely unknown. In this stu...

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Bibliographic Details

Published in:	Molecular Therapy: Nucleic Acids
Main Authors:	Shunshun Han, Can Cui, Xiyu Zhao, Yao Zhang, Yun Zhang, Jing Zhao, Xiaoxu Shen, Haorong He, Jianping Wang, Menggen Ma, Diyan Li, Qing Zhu, Huadong Yin
Format:	Article
Language:	English
Published:	Elsevier 2022-03-01
Subjects:	filamin C skeletal muscle atrophy dishevelled-2 autophagy mitophagy
Online Access:	http://www.sciencedirect.com/science/article/pii/S2162253121002973