Dioscin Protects against Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling

Acute kidney injury (AKI) is a clinical syndrome with high morbidity and mortality worldwide, and there is currently no effective means to prevent it. Dioscin is naturally present in the dioscoreaceae plants and has antioxidant and anti-inflammatory effects. Here, we found that dioscin is protective...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Shuang Wang, Yingce Zheng, Shengzi Jin, Yunwei Fu, Yun Liu
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Subjects:	acute kidney injury dioscin oxidative stress apoptosis ferroptosis Nrf2/HO-1 signaling
Online Access:	https://www.mdpi.com/2076-3921/11/12/2443