Cytomegalovirus infection exacerbates autoimmune mediated neuroinflammation

Abstract Cytomegalovirus (CMV) is a latent virus which causes chronic activation of the immune system. Here, we demonstrate that cytotoxic and pro-inflammatory CD4+CD28null T cells are only present in CMV seropositive donors and that CMV-specific Immunoglobulin (Ig) G titers correlate with the perce...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Marjan Vanheusden, Bieke Broux, Suzanne P. M. Welten, Liesbet M. Peeters, Eleni Panagioti, Bart Van Wijmeersch, Veerle Somers, Piet Stinissen, Ramon Arens, Niels Hellings
Format: Article
Language:English
Published: Nature Portfolio 2017-04-01
Online Access:https://doi.org/10.1038/s41598-017-00645-3