C-reactive protein conformations and their association with the IL-1β/IL-6 pathway in ocular inflammatory conditions

IntroductionC-reactive protein (CRP) plays a critical role in the innate immune system and serves as a biomarker for various inflammatory conditions. CRP is a dynamic protein undergoing conformational changes between pentameric (pCRP) and monomeric (mCRP) conformations. pCRP is the well-established...

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الحاوية / القاعدة:	Frontiers in Immunology
المؤلفون الرئيسيون:	Mercedes S. Nabaes Jodar, Víctor Llorenç, Marc Figueras-Roca, Maite Sainz de-la-Maza, Alfredo Adán, Blanca Molins
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2025-05-01
الموضوعات:	C-reactive protein (CRP) interleukin-1β (IL-1β) interleukin-6 (IL-6) ocular inflammation uveitis diabetic macular edema
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1601145/full