The Rip1 intramembrane protease contributes to iron and zinc homeostasis in Mycobacterium tuberculosis

ABSTRACT Mycobacterium tuberculosis is exposed to a variety of stresses during a chronic infection, as the immune system simultaneously produces bactericidal compounds and starves the pathogen of essential nutrients. The intramembrane protease, Rip1, plays an important role in the adaptation to thes...

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Bibliographic Details

Published in:	mSphere
Main Authors:	Samantha J. Nelson, John T. Williams, John A. Buglino, Subhalaxmi Nambi, Lisa J. Lojek, Michael S. Glickman, Thomas R. Ioerger, Christopher M. Sassetti
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-08-01
Subjects:	iron homeostasis nutritional immunity Mycobacterium tuberculosis zinc sigma factors
Online Access:	https://journals.asm.org/doi/10.1128/msphere.00389-22