Abraham Model Solute Descriptors for Favipiravir: Case of Tautomeric Equilibrium and Intramolecular Hydrogen-Bond Formation

Experiment-based Abraham model solute descriptors are calculated based on recently published solubility data for favipiravir dissolved in 12 chemically diverse organic mono-solvents. The calculated descriptor values indicate that favipiravir engages in intramolecular hydrogen formation that renders...

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Bibliographic Details
Published in:Thermo
Main Authors: Emily Yao, William E. Acree
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Subjects:
Abraham model
intramolecular hydrogen-bond formation
favipiravir
solute descriptors
keto-enol tautomerism
Online Access:https://www.mdpi.com/2673-7264/3/3/27

Internet

https://www.mdpi.com/2673-7264/3/3/27

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