Akt-ing Up Just About Everywhere: Compartment-Specific Akt Activation and Function in Receptor Tyrosine Kinase Signaling

The serine/threonine kinase Akt is a master regulator of many diverse cellular functions, including survival, growth, metabolism, migration, and differentiation. Receptor tyrosine kinases are critical regulators of Akt, as a result of activation of phosphatidylinositol-3-kinase (PI3K) signaling lead...

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發表在:	Frontiers in Cell and Developmental Biology
Main Authors:	Michael G. Sugiyama, Gregory D. Fairn, Costin N. Antonescu
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2019-05-01
主題:	receptor tyrosine kinase endocytosis plasma membrane endosome lysosome nucleus
在線閱讀:	https://www.frontiersin.org/article/10.3389/fcell.2019.00070/full