Prediction of Low-Dose Aspirin-Induced Gastric Toxicity Using Nuclear Magnetic Resonance Spectroscopy-Based Pharmacometabolomics in Rats

Background: Low-dose aspirin (LDA) is the backbone for secondary prevention of coronary artery disease, although limited by gastric toxicity. This study aimed to identify novel metabolites that could predict LDA-induced gastric toxicity using pharmacometabolomics. Methods: Pre-dosed urine samples we...

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書誌詳細

出版年:	Molecules
主要な著者:	Abubakar Sha’aban, Hadzliana Zainal, Nor Azlina Khalil, Fatimatuzzahra’ Abd Aziz, Ewe Seng Ch’ng, Chin-Hoe Teh, Mustapha Mohammed, Baharudin Ibrahim
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2022-03-01
主題:	aspirin pharmacometabolomic nuclear magnetic resonance spectroscopy gastric toxicity multivariate analysis
オンライン･アクセス:	https://www.mdpi.com/1420-3049/27/7/2126