Causes, consequences and clinical significance of aneuploidy across melanoma subtypes

Aneuploidy, the state of the cell in which the number of whole chromosomes or chromosome arms becomes imbalanced, has been recognized as playing a pivotal role in tumor evolution for over 100 years. In melanoma, the extent of aneuploidy, as well as the chromosomal regions that are affected differ ac...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Eva R. Shteinman, James S. Wilmott, Ines Pires da Silva, Georgina V. Long, Richard A. Scolyer, Ismael A. Vergara
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Subjects:	melanoma aneuploidy chromosome missegregation driver mutations diagnosis prognosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2022.988691/full