Regulating the proinflammatory response to composite biomaterials by targeting immunometabolism

Composite biomaterials comprising polylactide (PLA) and hydroxyapatite (HA) are applied in bone, cartilage and dental regenerative medicine, where HA confers osteoconductive properties. However, after surgical implantation, adverse immune responses to these composites can occur, which have been attr...

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Bibliographic Details

Published in:	Bioactive Materials
Main Authors:	Chima V. Maduka, Ashley V. Makela, Anthony Tundo, Evran Ural, Katlin B. Stivers, Maxwell M. Kuhnert, Mohammed Alhaj, Ehsanul Hoque Apu, Nureddin Ashammakhi, Kurt D. Hankenson, Ramani Narayan, Jennifer H. Elisseeff, Christopher H. Contag
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2024-10-01
Subjects:	Hydroxyapatite Polylactide Immunometabolism Inflammation Regenerative medicine
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452199X24002123