Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration

Increasing evidence suggests that neurodegenerative disorders share a common pathogenic feature: the presence of deposits of misfolded proteins with altered physicochemical properties in the Central Nervous System. Despite a lack of infectivity, experimental data show that the replication and propag...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Carlo Scialò, Elena De Cecco, Paolo Manganotti, Giuseppe Legname
Format:	Article
Language:	English
Published:	MDPI AG 2019-03-01
Subjects:	prion prion-like proteins strains neurodegeneration
Online Access:	http://www.mdpi.com/1999-4915/11/3/261