Life at the crossroads: the nuclear LINC complex and vascular mechanotransduction

Vascular endothelial cells line the inner surface of all blood vessels, where they are exposed to polarized mechanical forces throughout their lifespan. Both basal substrate interactions and apical blood flow-induced shear stress regulate blood vessel development, remodeling, and maintenance of vasc...

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Bibliographic Details
Published in:Frontiers in Physiology
Main Authors: Pauline Bougaran, Victoria L. Bautch
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1411995/full