The replicative CMG helicase: the ideal target for cancer therapy
This review focuses on Cdc45-Mcm2-7-GINS (CMG) helicase which is a key component of the cellular replication machinery and a new promising target for cancer therapy. In normal cells, only a small proportion of helicases becomes activated through the step-wise acquisition of all necessary subunits d...
| 出版年: | The Ukrainian Biochemical Journal |
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| 主要な著者: | , , , |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2020-12-01
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| 主題: | |
| オンライン･アクセス: | http://ukrbiochemjournal.org/wp-content/uploads/2020/12/Henderson_6_20.pdf |