The challenge of producing skin test antigens with minimal resources suitable for human application against a neglected tropical disease; leprosy.

True incidence of leprosy and its impact on transmission will not be understood until a tool is available to measure pre-symptomatic infection. Diagnosis of leprosy disease is currently based on clinical symptoms, which on average take 3-10 years to manifest. The fact that incidence, as defined by n...

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Bibliographic Details

Published in:	PLoS Neglected Tropical Diseases
Main Authors:	Becky L Rivoire, Stephen TerLouw, Nathan A Groathouse, Patrick J Brennan
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Online Access:	https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0002791&type=printable