Intradermal DNA vaccine delivery using vacuum-controlled, needle-free electroporation

Intradermal delivery of DNA vaccines via electroporation (ID-EP) has shown clinical promise, but the use of needle electrodes is typically required to achieve consistent results. Here, delivery of a DNA vaccine targeting the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is achieved using n...

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Bibliographic Details

Published in:	Molecular Therapy: Nucleic Acids
Main Authors:	Alison Generotti, Ryne Contreras, Brenden Zounes, Eric Schade, Andrea Kemme, Yatish Rane, Xinggang Liu, Dustin Elwood, Katherine Schultheis, Jeremy Marston, Jay McCoy, Kate Broderick, Paul Fisher
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Subjects:	MT: Delivery Strategies Electroporation DNA vaccine nucleic acid delivery transfection skin
Online Access:	http://www.sciencedirect.com/science/article/pii/S2162253123002883