Clinical features and genetic analysis of nine Chinese children with Dent disease and identification of three novel CLCN5 and OCRL variants

Objective This study aims to elucidate the genetic and phenotypic characteristics of pediatric patients with potential Dent disease (DD).Methods High-throughput sequencing was conducted on 11 pediatric patients with potential cases of DD. We also analyzed clinical phenotype and treatment regimens.Re...

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Bibliographic Details

Published in:	Renal Failure
Main Authors:	Xinyi Jiang, Hongzhou Lin, Qifan Zhu, Huihui Chen, Yutong Huang, Xiu-Feng Huang, Dexuan Wang
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Dent disease CLCN5 OCRL proteinuria children
Online Access:	https://www.tandfonline.com/doi/10.1080/0886022X.2025.2476222