Generation of induced pluripotent stem cells, KCi005-A derived from a female with Parkinsońs disease and homozygous for the PINK1 variant c.1366C > T, p.Gln456*

Disease causing variants in several genes including PINK1 have been identified in hereditary Parkinsońs disease (PD). The mechanism behind this neuronal degeneration is not clarified but it is assumed that mitochondrial dysfunction, e.g. oxidative stress, might be involved. Here we describe the gen...

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Bibliographic Details

Published in:	Stem Cell Research
Main Authors:	Lasse Jonsgaard Larsen, Lena Elisabeth Hjermind, Lisbeth Birk Møller
Format:	Article
Language:	English
Published:	Elsevier 2024-02-01
Subjects:	PINK1 iPSC Mitochondria Parkinsońs
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506123002659