Krt14 and Krt15 differentially regulate regenerative properties and differentiation potential of airway basal cells

Keratin expression dynamically changes in airway basal cells (BCs) after acute and chronic injury, yet the functional consequences of these changes on BC behavior remain unknown. In bronchiolitis obliterans (BO) after lung transplantation, BC clonogenicity declines, which is associated with a switch...

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Bibliographic Details

Published in:	JCI Insight
Main Authors:	Vitaly Ievlev, Thomas J. Lynch, Kyle W. Freischlag, Caitlyn B. Gries, Anit Shah, Albert C. Pai, Bethany A. Ahlers, Soo Park, John F. Engelhardt, Kalpaj R. Parekh
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2023-01-01
Subjects:	Pulmonology Stem cells
Online Access:	https://doi.org/10.1172/jci.insight.162041