Neutrophil Activation in Acute Hemorrhagic Fever With Renal Syndrome Is Mediated by Hantavirus-Infected Microvascular Endothelial Cells

Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) in humans. Both diseases are considered to be immunologically mediated but the exact pathological mechanisms are still poorly understood. Neutrophils are considered the first line of defens...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Tomas Strandin, Satu Mäkelä, Jukka Mustonen, Antti Vaheri
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-09-01
Subjects:	hantavirus HFRS neutrophils IL-8 endothelial cells degranulation
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2018.02098/full