The potential of using itaconate as treatment for inflammation-related heart diseases

Intracellular metabolites can cause critical changes in biological functions. Itaconate is perhaps the most fascinating substance in macrophages. Lipopolysaccharide can activate aconitate decarboxylase 1 and induces the generation of itaconate from the tricarboxylic acid cycle by decarboxylation of...

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Bibliographic Details

Published in:	Tzu Chi Medical Journal
Main Authors:	Hui-Chen Ku, Ta-Chung Shen, Ching-Feng Cheng
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2022-01-01
Subjects:	activating transcription factor 3 inflammation itaconate nuclear factor erythroid 2-related factor 2 succinate dehydrogenase
Online Access:	http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2022;volume=34;issue=2;spage=113;epage=118;aulast=Ku