Inflammatory and homeostatic roles of eosinophil subpopulations in chronic rhinosinusitis with nasal polyp pathogenesis

Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) mainly expresses type-2 endotype, featuring eosinophils as a main player in the inflammatory process. Prolonged eosinophilia in the tissues of asthma and CRSwNP patients has been associated with structural changes, leading to fixed airflow obst...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Kantapat Simmalee, Putthapoom Lumjiaktase, Theerasuk Kawamatawong, Amir Guemari, Valérian Dormoy, Joana Vitte
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	chronic rhinosinusitis with nasal polyps eosinophil eosinophil subpopulations inflammatory eosinophils resident eosinophils
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1568541/full