CREB coactivator CRTC1 in melanocortin‐4 receptor‐expressing cells regulate dietary fat intake

Abstract Cyclic adenosine monophosphate‐response element‐binding protein‐1‐regulated transcription coactivator‐1 (CRTC1), a cytoplasmic coactivator that translocates to the nucleus in response to cAMP, is associated with obesity. We previously reported that CRTC1 deficiency in melanocortin‐4 recepto...

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Bibliographic Details

Published in:	FASEB BioAdvances
Main Authors:	Shigenobu Matsumura, Miyu Fujisawa, Mizuki Fujiwara, Houko Okayama, Miona Marutani, Eri Nousou, Tsutomu Sasaki, Naoki Harada
Format:	Article
Language:	English
Published:	Wiley 2024-12-01
Subjects:	aging appetite dietary fat gene expression metabolism obesity
Online Access:	https://doi.org/10.1096/fba.2024-00111