DESIGN, SYNTHESIS, BIOLOGICAL EVALUATION, AND IN SILICO STUDY OF NOVEL UREA DERIVATIVES AS INHIBITORS OF CARBONIC ANHYDRASE AND ACETYLCHOLINE ESTERASE

This study aimed to synthesize novel unsymmetrical urea derivatives containing biologically active tryptamine and phenethylamines and investigate their inhibition effects on human carbonic anhydrase (hCA) I and II isozymes as well as acetylcholinesterase (AChE). For this purpose, five different N,N...

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Bibliographic Details

Published in:	Studia Universitatis Babes-Bolyai Chemia
Main Authors:	Yusuf AKBABA, Ramazan KALIN
Format:	Article
Language:	English
Published:	Babes-Bolyai University 2022-06-01
Subjects:	biological activity, tryptamine, phenethylamine, toxicology, molecular docking, ADME.
Online Access:	https://studia.reviste.ubbcluj.ro/index.php/chemia/article/view/7783