Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models

Abstract Background Particular breast cancer subtypes pose a clinical challenge due to limited targeted therapeutic options and/or poor responses to the existing targeted therapies. While cell lines provide useful pre-clinical models, patient-derived xenografts (PDX) and organoids (PDO) provide sign...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Breast Cancer Research
المؤلفون الرئيسيون:	Nicole J. Chew, Terry C. C. Lim Kam Sian, Elizabeth V. Nguyen, Sung-Young Shin, Jessica Yang, Mun N. Hui, Niantao Deng, Catriona A. McLean, Alana L. Welm, Elgene Lim, Peter Gregory, Tim Nottle, Tali Lang, Melissa Vereker, Gary Richardson, Genevieve Kerr, Diana Micati, Thierry Jardé, Helen E. Abud, Rachel S. Lee, Alex Swarbrick, Roger J. Daly
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2021-08-01
الموضوعات:	Targeted therapy Oncogene Fibroblast growth factor receptor SKI proto-oncogene Precision oncology
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13058-021-01461-4