Follicle-intrinsic and spatially distinct molecular programs drive follicle rupture and luteinization during ex vivo mammalian ovulation

Abstract During ovulation, the apical wall of the preovulatory follicle breaks down to facilitate gamete release. In parallel, the residual follicle wall differentiates into a progesterone-producing corpus luteum. Disruption of ovulation, whether through contraceptive intervention or infertility, ha...

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Bibliographic Details
Published in:Communications Biology
Main Authors: Emily J. Zaniker, Jiyang Zhang, Daniela Russo, Ruixu Huang, Kristine Suritis, Riley S. Drake, Esther Barlow-Smith, Alex K. Shalek, Teresa K. Woodruff, Shuo Xiao, Brittany A. Goods, Francesca E. Duncan
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Online Access:https://doi.org/10.1038/s42003-024-07074-9