Identification of Splicing Regulatory Activity of ATXN1 and Its Associated Domains
The expansion of the polyglutamine tract in ATXN1 contributes to the pathogenesis of SCA1. ATXN1 functions as a transcriptional regulator that interacts with multiple transcription factors, and transcriptional dysregulation has been observed in SCA1. In addition, splicing dysregulation has been iden...
| الحاوية / القاعدة: | Biomolecules |
|---|---|
| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
MDPI AG
2025-05-01
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://www.mdpi.com/2218-273X/15/6/782 |