Pleckstrin homology-like domain family A, member 3 (PHLDA3) deficiency improves islets engraftment through the suppression of hypoxic damage.

Islet transplantation is a useful cell replacement therapy that can restore the glycometabolic function of severe diabetic patients. It is known that many transplanted islets failed to engraft, and thus, new approaches for overcoming graft loss that may improve the outcome of future clinical islet t...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Naoaki Sakata, Yohko Yamaguchi, Yu Chen, Masayuki Shimoda, Gumpei Yoshimatsu, Michiaki Unno, Shoichiro Sumi, Rieko Ohki
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2017-01-01
Online Access:	http://europepmc.org/articles/PMC5679611?pdf=render