Risk of autoimmunity, cancer seeding, and adverse events in human trials of whole-tissue autologous therapeutic vaccines

Background: Whole-tissue autologous therapeutic vaccines (WATVs) are a form of cancer immunotherapy that use a patient's own pathological tissue. Concerns exist regarding the potential of WATVs to induce autoimmunity or the spread of cancer; however, their adverse events (AEs) have not been ade...

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Bibliographic Details

Published in:	Cancer Pathogenesis and Therapy
Main Authors:	Garrett Gianneschi, Anthony Scolpino, James Oleske
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Subjects:	Neoplasms Vaccination Autoimmunity Immunotherapy Drug-related side effects and adverse reactions Systematic review
Online Access:	http://www.sciencedirect.com/science/article/pii/S2949713224000326