Active antithrombin glycoforms are selectively physiosorbed on plasma extracellular vesicles

Abstract Antithrombin (AT) is a glycoprotein produced by the liver and a principal antagonist of active clotting proteases. A deficit in AT function leads to AT qualitative deficiency, challenging to diagnose. Here we report that active AT may travel physiosorbed on the surface of plasma extracellul...

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Bibliographic Details

Published in:	Journal of Extracellular Biology
Main Authors:	Annalisa Radeghieri, Silvia Alacqua, Andrea Zendrini, Vanessa Previcini, Francesca Todaro, Giuliana Martini, Doris Ricotta, Paolo Bergese
Format:	Article
Language:	English
Published:	Wiley 2022-09-01
Subjects:	antithrombin extracellular vesicles glycosylation protein corona
Online Access:	https://doi.org/10.1002/jex2.57