Imaging Protein Misfolding in the Brain Using β-Sheet Ligands

Neurodegenerative diseases characterized by pathological protein accumulation in cells are termed “proteinopathies.” Although various protein aggregates share cross-β-sheet structures, actual conformations vary among each type of protein deposit. Recent progress in the development of radiotracers fo...

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Bibliographic Details

Published in:	Frontiers in Neuroscience
Main Authors:	Ryuichi Harada, Nobuyuki Okamura, Shozo Furumoto, Kazuhiko Yanai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-08-01
Subjects:	proteinopathies protein aggregates β-sheet ligands PET tau
Online Access:	https://www.frontiersin.org/article/10.3389/fnins.2018.00585/full