Coordinated local RNA overexpression of complement induced by interferon gamma in myositis

Abstract Complement proteins are deposited in the muscles of patients with myositis. However, the local expression and regulation of complement genes within myositis muscle have not been well characterized. In this study, bulk RNA sequencing (RNAseq) analyses of muscle biopsy specimens revealed that...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Maria Casal-Dominguez, Iago Pinal-Fernandez, Katherine Pak, Sandra Muñoz-Braceras, Jose C. Milisenda, Jiram Torres-Ruiz, Stefania Dell′Orso, Faiza Naz, Gustavo Gutierrez-Cruz, Yaiza Duque-Jaimez, Ana Matas-Garcia, Laura Valls-Roca, Gloria Garrabou, Ernesto Trallero-Araguas, Brian Walitt, Lisa Christopher-Stine, Thomas E. Lloyd, Julie J. Paik, Jemima Albayda, Andrea Corse, Josep Maria Grau, Albert Selva-O’Callaghan, Andrew L. Mammen
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Online Access:https://doi.org/10.1038/s41598-023-28838-z

Internet

https://doi.org/10.1038/s41598-023-28838-z

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