SFTSV NSs interacts with AGO2 to regulate the RNAi pathway for viral replication

ABSTRACT RNA interference (RNAi) is a posttranscriptional gene silencing mechanism acting as an antiviral defense in eukaryotes. During viral replication, intermediate double-stranded RNAs are processed into virus-derived small interfering RNAs (vsiRNAs) by the host enzyme, DICER. These vsiRNAs are...

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Bibliographic Details
Published in:Journal of Virology
Main Authors: Nasir Javaid, Tae-Won Jang, Yuting Fu, Younho Choi
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Subjects:
SFTSV
nonstructural protein
RNAi
viral replication
bunyavirus
Online Access:https://journals.asm.org/doi/10.1128/jvi.02205-24

Internet

https://journals.asm.org/doi/10.1128/jvi.02205-24

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