An Intramolecular Hydroaminomethylation-Based Approach to Pyrrolizidine Alkaloids under Microwave-Assisted Heating

A general method for the synthesis of pyrrolizidine derivatives using an intramolecular hydroaminomethylation protocol (HAM) under microwave (MW) dielectric heating is reported. Starting from a 3,4-bis(benzyloxy)-2-[(benzyloxy)methyl]-5-vinylpyrrolidine, MW-assisted intramolecular HAM in the presenc...

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Bibliographic Details
Published in:Molecules
Main Authors: Elena Petricci, Simone Zurzolo, Camilla Matassini, Samuele Maramai, Francesca Cardona, Andrea Goti, Maurizio Taddei
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Subjects:
pyrrolizidine alkaloid
hydroaminomethylation
hydroformylation
microwave-assisted organic synthesis
Online Access:https://www.mdpi.com/1420-3049/27/15/4762

Internet

https://www.mdpi.com/1420-3049/27/15/4762

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