Transient activation of YAP/TAZ confers resistance to morusin-induced apoptosis

Abstract Background The Hippo signaling pathway involves a kinase cascade that controls phosphorylation of the effector proteins YAP and TAZ, leading to regulation of cell growth, tissue homeostasis, and apoptosis. Morusin, a compound extracted from Morus alba, has shown potential in cancer therapy...

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Published in:	BMC Molecular and Cell Biology
Main Authors:	Hoyeon Lee, Sang Woo Cho, Hyo Sun Cha, Kun Tae, Cheol Yong Choi
Format:	Article
Language:	English
Published:	BMC 2025-01-01
Subjects:	YAP/TAZ Morusin Stress granule Apoptosis
Online Access:	https://doi.org/10.1186/s12860-025-00531-1