A novel in vitro model to study prolonged Pseudomonas aeruginosa infection in the cystic fibrosis bronchial epithelium.

Pseudomonas aeruginosa (PA) is known to chronically infect airways of people with cystic fibrosis (CF) by early adulthood. PA infections can lead to increased airway inflammation and lung tissue damage, ultimately contributing to decreased lung function and quality of life. Existing models of PA inf...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Meghan J Hirsch, Emily M Hughes, Molly M Easter, Seth E Bollenbecker, Patrick H Howze Iv, Susan E Birket, Jarrod W Barnes, Megan R Kiedrowski, Stefanie Krick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0288002&type=printable