Trpv6 channel targeting using monoclonal antibody induces prostate cancer cell apoptosis and tumor regression

Abstract TRPV6 calcium channel is a prospective target in prostate cancer (PCa) since it is not expressed in healthy prostate while its expression increases during cancer progression. Despite the role of TRPV6 in PCa cell survival and apoptotic resistance has been already established, no reliable to...

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Bibliographic Details

Published in:	Cell Death and Disease
Main Authors:	Aurélien Haustrate, Clément Cordier, George Shapovalov, Adriana Mihalache, Emilie Desruelles, Benjamin Soret, Nadège Charlène Essonghé, Corentin Spriet, Maya Yassine, Alexandre Barras, Johanna Marines, Lindsay B. Alcaraz, Sabine Szunerits, Gautier Robin, Pierre Gosset, Natalia Prevarskaya, V’yacheslav Lehen’kyi
Format:	Article
Language:	English
Published:	Nature Publishing Group 2024-06-01
Online Access:	https://doi.org/10.1038/s41419-024-06809-0