Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer’s disease

DNA methylation differences in Alzheimer’s disease have been previously reported, although the interpretation of the differences is unclear. Here, the authors performed epigenome-wide meta-analyses of DNA methylation in blood and brain, and developed a methylation-based risk prediction model for AD....

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Bibliographic Details
Published in:Nature Communications
Main Authors: Tiago C. Silva, Juan I. Young, Lanyu Zhang, Lissette Gomez, Michael A. Schmidt, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Online Access:https://doi.org/10.1038/s41467-022-32475-x