Polyphotosensitizer‐Based Nanoparticles with Michael Addition Acceptors Inhibiting GST Activity and Cisplatin Deactivation for Enhanced Chemotherapy and Photodynamic Immunotherapy

Abstract Glutathione S‐transferase (GST), which is a key enzyme in the conjugation reaction of glutathione (GSH), is overexpressed in cancer cells, leading to cisplatin deactivation and ultimately drug resistance. In addition, many tumors are immune “cold tumors,” limiting the application of immune...

Full description

Bibliographic Details

Published in:	Advanced Science
Main Authors:	Qinxin Zhao, Ganghao Liang, Boda Guo, Wenkuan Wang, Chao Yang, Dong Chen, Feiya Yang, Haihua Xiao, Nianzeng Xing
Format:	Article
Language:	English
Published:	Wiley 2023-05-01
Subjects:	chemotherapy immunotherapy Michael addition acceptor nanoparticles photodynamic prostate cancer
Online Access:	https://doi.org/10.1002/advs.202300175