Sequential conformational rearrangements in flavivirus membrane fusion

The West Nile Virus (WNV) envelope protein, E, promotes membrane fusion during viral cell entry by undergoing a low-pH triggered conformational reorganization. We have examined the mechanism of WNV fusion and sought evidence for potential intermediates during the conformational transition by followi...

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Bibliographic Details
Published in:eLife
Main Authors: Luke H Chao, Daryl E Klein, Aaron G Schmidt, Jennifer M Peña, Stephen C Harrison
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-12-01
Subjects:
membrane fusion
flavivirus
West Nile virus
single particle
kinetic
conformational change
Online Access:https://elifesciences.org/articles/04389

Internet

https://elifesciences.org/articles/04389

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